What Medications Can Interfere with Cervical Mucus?

What Medications Can Interfere with Cervical Mucus?

What Is Cervical Mucus?

When you are trying to conceive, you will quickly learn how important cervical mucus is to conception. Cervical mucus is the gel like substance that a woman’s body produces and secretes naturally. Cervical mucus can be both good and bad. Claim Your 20 Free Pregnancy Tests – Click Here

Good cervical mucus will help to protect the sperm and guide them on their journey to fertilize the egg. Bad cervical mucus, also known as hostile cervical mucus, will actually hurt the sperm. If a woman has good cervical mucus, it will help her to get pregnant. However, if a woman has hostile cervical mucus or no cervical mucus, then it can be really hard for her to get pregnant.

Medications that can interfere

Sometimes, medications can interfere with the production of cervical mucus, making it into hostile cervical mucus and sometimes making cervical mucus nonexistent. These medications aren’t always the ones that you would expect, so you might not know which ones to avoid and which ones are okay. Let’s talk about some of those medications so you will know to look out for them.


Clomid is one of the most common medications that affects cervical mucus. Clomid is one of the most popular and commonly prescribed pills to get pregnant as a first course of infertility treatment, and it can help women ovulate pretty easily. However, it can have a negative affect on cervical mucus, and can even make good cervical mucus (egg white cervical mucus) turn into hostile cervical mucus.

If your doctor prescribes Clomid, make sure to ask him or her what you can do to keep your cervical mucus from turning hostile. They will be able to offer some tips for you, to help your cervical mucus stay at the optimal conditions.


Guafenisen is often found in cough syrups like Robitussin. Guafenisen is one of the medications that can affect cervical mucus, but not like you might think. Guafenisen is actually one of the few medications that can improve cervical mucus.

Something in the cough syrup prevents hostile cervical mucus from forming, and can even help egg white cervical mucus to be produced. (Egg white cervical mucus is the good kind of cervical mucus.) Sometimes doctors even recommend that women taking Clomid also use Robitussin to offset the negative effects that Clomid can have on cervical mucus.

Antihistamines or Allergy Medications

Antihistamines and allergy medications like Benadryl can also sometimes cause problems with cervical mucus. This is because these medications help to “dry up” mucus and fluid in the nose and throat in order to help alleviate allergy problems. When this occurs, the allergy medications also can dry up cervical mucus. For this reason, doctors usually recommend that women who are trying to conceive do not take antihistamines or allergy medications.

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Alyssia Granger
Alyssia Granger | ConceiveEasy
Alyssia is mom to 2 giggley twin girls, Sophia and Emma, and son Hunter. She's a Southern girl, passionate about photography, travel and her husband Josh.