Clomid: Possible Side Effects

on Nov 16, 2012

by Maureen Stephens, BS, RN

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Clomid: Possible Side Effects

Clomid is one of the most popular drugs used in the treatment of infertility, but it is not without its side effects.

Clomid is one of the most renowned drugs used in the treatment of infertility issues. As efficient as it is in this respect, like any other fertility drug, Clomid side effects do exist. However, their manifestation is usually not a worrying problem. Here are the most common reactions to this drug Claim Your 20 Free Pregnancy Tests – Click Here

Multiple pregnancy

The most widespread byproduct is multiple pregnancy. More accurately, clinical trials of Clomid proved that 6.9% are twin pregnancies, 0.5% are triplets, 0.3% are quadruplets and 0.1% quintuplets. In order to avoid this complication, you should start taking the drug in the lowest dose at first (50 mg). However, many see this as a boon, going from struggling with infertility to a blessing times two, three or more.

Hot flashes

Hot flashes are also common, being experienced by about 10% of the women who use this drug. The symptoms implied here are the feeling of sudden warmth, breaking out in sweat and increased heartbeat. Also, after the hot flash, you might feel coldness in your body. Nevertheless, hot flashes are just uncomfortable occurrences, there is nothing dangerous involved here.


Women who use this particular medicine may gain weight, but only 1% of them experience this. It might be connected to bloating, another side effect of taking this drug. Any case, weight gain is related to this, it is highly likely it will go away after the termination of the treatment.

Mood swings

Mood swings may also occur if you use this drug, but it appears in less than 1% of the cases. What this implies is that women may feel overly sensitive emotionally speaking, anxious or even depressed.

Abnormal menstrual bleeding

Abnormal menstrual bleeding is one of the side effects, with an occurrence of more than 1%, but it should normally just feel uncomfortable. When taking fertility drugs it is normal for women to have their menstrual cycle messed up. However, if you notice other dysfunctions like abdominal pain, vomiting, fever or nausea, you should immediately contact your doctor.

Vaginal dryness or thick cervical mucus

Vaginal dryness or thick cervical mucus sometimes occur after the use of this drug, which is upsetting as the absence of cervical fluid can harm the process of getting pregnant. Cervical mucus is essential in carrying the sperm through the cervix. There are, of course, ways to bypass this problem or you can simply talk to your doctor and he or she will change the medication.

As a conclusion, this drug is very useful in fertility treatment, but you should pay attention of possible side effects, as they are quite varied. Nonetheless, Clomid side effects are mild and usually they do not get serious, and if they do, then you can just consult your doctor and ask for change of treatment.

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Clomid: Possible Side Effects, 4.8 out of 5 based on 6 ratings

Ms. Stephens has spent over twenty years in the healthcare world, specializing in obstretical and medical/surgical nursing. She joined ConceiveEasy as she has a strong interest in educating and empowering women and promoting fertility awareness.

  • Regina

    pls am feeling some pains in my lower belly some weeks after i was dis virgin and i lean that am urinating some more time and could not sleep well , please could this be that am pregnant

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  • Dr. Prabha Sahgal, MD

    Since abdomen cramps, frequent urination and fatigue are considered to be early symptoms of pregnancy, there is a good chance for you to be pregnant. These pregnancy symptoms are commonly due to your high levels of estrogen and progesterone that occurs during pregnancy. Once you have missed your period already, you should try to take a pregnancy test after 14 days for a reliable result.

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  • sagitarian

    im also experiencing frequent urination after my 1st round of clomid 50mg, not sure if this one of its side effect but i only experience this after taking the med. Were ttc for almost 1 year & ob prescribed this to me me since im not ovulating regularly.

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