PCOS is short for Polycystic Ovarian Syndrome and it inflicts about five percent of the women. Women who suffer with PCOS have higher than normal levels of androgen, which is the male hormone. Additionally, their ovaries consist of cysts. Claim Your 20 Free Pregnancy Tests – Click Here
Their main problem is that they don’t ovulate. This is the reason why they fail to get pregnant. Symptoms of this female hormonal disorder include extra body hair, hirsuitism, and acne. These symptoms are because of the higher levels of androgen. Most women suffering with PCOS tend to be obese or overweight.
There are many different treatments for PCOS and they depend on the situation of the patient. For example, treatments are different for women who want to get pregnant from those who don’t want to get pregnant.
Clomid is an oral drug, which is given to treat PCOS in women who are looking to get pregnant. It is a prescription drug, which is anti-estrogen. It works to stimulate ovulation by stimulating the ovaries so that they produce eggs and this is how it helps those with PCOS to get pregnant.
Ovulation is carried out and regulated by four different hormones, mainly. These are: progesterone, estrogen, luteinizing hormone, and follicle stimulating hormone. They work in a very intricate and balanced manner to regulate ovulation.
Their working is based on negative feedback mechanism. In other words, when the levels of one hormone come down, a signal is sent to increase the levels of another. The levels of estrogen need to go down in order for the LH and FSH hormones to rise in quantity.
These two hormones are responsible for the maturation of the egg. What Clomid does is, it binds to the receptors of estrogen, and as a result, the body thinks that the estrogen levels are low. Thus, FSH and LH are released in large quantities and ovulation occurs.
Usually, Clomid is given for five days a month continuously. The dosage begins around three days after the first day of your menstrual cycle. You need about 50mg of Clomid to begin with. If the months go by and pregnancy still does not occur, the dosage may be increased to 100mg. Sometimes even high doses of Clomid are given based on the requirements and the situation presented.
The success rate of this drug is 73% but that percentage is with respect to ovulation. Remember that ovulation does not guarantee pregnancy. While 73% start ovulating once they take this medication, only about 36% end up getting pregnant. Estrogen works to thicken the uterine lining, which is very important for implantation of the fertilized egg.
When the levels of estrogen are lower, thickening may not occur sometimes and implantation may get difficult. In some cases, Clomid also interferes with the cervical mucus secretion. If the cervical mucus is not present, the sperm won’t be able to reach the egg successfully.
Clomid comes with a few side effects. The main side effect is hot flashes. Depression, vaginal dryness, fatigue, nausea, and headache are the other side effects. You might also experience heavy bleeding once you take Clomid because you have started ovulating. You will increase your chances of twins by 10% if you take Clomid.