How Does PCOS Affect Fertility?

How Does PCOS Affect Fertility?

PCOS (Polycystic Ovarian Syndrome) is a physical condition involving the hormonal imbalance of the female body, currently affecting almost 10% of adult women. This condition is closely related to the imbalance in the secretion of progesterone, estrogen and androgen as well, disrupting the healthy ovulation cycle of the woman.  Claim Your 20 Free Pregnancy Tests – Click Here

PCOS and infertility are closely linked: the fertilization of the egg needs healthy egg production, and, if the ovulation cycle becomes compromised, the eggs are not matured or they fail to implant, leading to infertility.

The good news is that PCOS-related infertility is nowadays treated with a high success rate. How to get pregnant with PCOS is what we will focus on here. In the following lines we will make a short presentation of the 3 most common treatments used to regulate hormonal levels and facilitate conception.


Clomid is often the first choice of medical experts for treating PCOS-related infertility. The active ingredient of this prescription drug is Clomiphene Citrate, which facilitates the fertilization of the egg by inducing ovulation. Administered early during the patient’s menstrual period, usually between day 3 and 7 or day 5 and 9, this very efficient medicine will remedy anovulation in about 75% of the cases, the success rate of getting pregnant in Clomid-patients being about 50%.


As an estrogen-suppressant, this drug decreases the production of this hormone, which results in the production of the hormones stimulating the production of follicles. Just like Clomid, Femara also works by inducing ovulation, but Femera is frequently given to women who have adverse reactions to Clomid.


PCOS is, in many cases, related to insulin resistance; so, another way of treating this condition and aiding fertility as well is controlling the blood sugar levels. Used very efficiently in combination with Clomid, Metformin reduces the quantity of sugar produced in the liver and it regulates the ovulation cycle by reducing androgen levels. It also diminishes the risks of suffering a miscarriage and of developing diabetes during pregnancy in patients suffering from PCOS, and it has a beneficial effect over obesity as well.

PCOS and infertility are two physical conditions in close relationship with each other. Though the exact causes of PCOS are not yet known, and a cure that works for one woman may not work for another, the successful treatment of this syndrome often cures fertility problems.

The drugs mentioned above are available on prescription; it is very important to investigate all the causes of the infertility prior to undergoing treatment with any of these medications.

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Dr. Renee Hanton, MD
Dr. Renee Hanton, MD | ConceiveEasy
Dr. Renee Hanton is ConceiveEasy's Senior Physician with expertise in the diagnosis and treatment of infertility. Dr. Hanton specializes in the endocrine causes of infertility, such as polycystic ovary syndrome (PCOS)