How Does PCOS Affect Fertility?

on Sep 15, 2012

by Dr. Renee Hanton, MD

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Find out how PCOS can cause infertility in women, how it is treated, and the success rates for getting pregnant for women with polycystic ovarian syndrome.

PCOS (Polycystic Ovarian Syndrome) is a physical condition involving the hormonal imbalance of the female body, currently affecting almost 10% of adult women. This condition is closely related to the imbalance in the secretion of progesterone, estrogen and androgen as well, disrupting the healthy ovulation cycle of the woman. PCOS and infertility are closely linked: the fertilization of the egg needs healthy egg production, and, if the ovulation cycle becomes compromised, the eggs are not matured or they fail to implant, leading to infertility. Claim Your 20 Free Pregnancy Tests – Click Here

The good news is that PCOS-related infertility is nowadays treated with a high success rate. In the following lines we will make a short presentation of the 3 most common treatments used to regulate hormonal levels and facilitate conception.


Clomid is often the first choice of medical experts for treating PCOS-related infertility. The active ingredient of this prescription drug is Clomiphene Citrate, which facilitates the fertilization of the egg by inducing ovulation. Administered early during the patient’s menstrual period, usually between day 3 and 7 or day 5 and 9, this very efficient medicine will remedy anovulation in about 75% of the cases, the success rate of getting pregnant in Clomid-patients being about 50%.


As an estrogen-suppressant, this drug decreases the production of this hormone, which results in the production of the hormones stimulating the production of follicles. Just like Clomid, Femera also works by inducing ovulation, but Femera is frequently given to women who have adverse reactions to Clomid.


PCOS is, in many cases, related to insulin resistance; so, another way of treating this condition and aiding fertility as well is controlling the blood sugar levels. Used very efficiently in combination with Clomid, Metformin reduces the quantity of sugar produced in the liver and it regulates the ovulation cycle by reducing androgen levels. It also diminishes the risks of suffering a miscarriage and of developing diabetes during pregnancy in patients suffering from PCOS, and it has a beneficial effect over obesity as well.

PCOS and infertility are two physical conditions in close relationship with each other. Though the exact causes of PCOS are not yet known, and a cure that works for one woman may not work for another, the successful treatment of this syndrome often cures fertility problems.

The drugs mentioned above are available on prescription; it is very important to investigate all the causes of the infertility prior to undergoing treatment with any of these medications.

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How Does PCOS Affect Fertility?, 4.8 out of 5 based on 8 ratings

Dr. Renee Hanton is ConceiveEasy's Senior Physician with expertise in the diagnosis and treatment of infertility. Dr. Hanton specializes in the endocrine causes of infertility, such as polycystic ovary syndrome (PCOS)

  • GeorginaW1

    How come we strugle since last year to get pregnant

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  • Dr. Renee Hanton, MD

    A preconception check-up is a suggested first step when you are planning to get pregnant, to ensure that you and your partner are healthy and to be able to address any pre-existing condition that can halt your plans of conceiving. It is highly recommended that you talk to your ObGyn to guide and oversee you on your journey to pregnancy and birth, in order to prevent any possible complications and assist you with a safe and healthy pregnancy. Good luck!

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  • VerneGrace

    I’ve been trying to get pregonant for 5 month already i checked in with obgyn any everything and yet nothing i try to keep a positive out put but i am growing impatient what natural things can i do to help get me pregnant?.

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  • Dr. Prabha Sahgal, MD

    One of the best ways to get pregnant faster is to have sex 2-3 days before ovulation. Sperm can live in your body for about 5 days while the ovum can survive for about 24 hours so you may want to give your man’s sperm a head start to boost their chances of reaching the ovum on time. Having a healthy lifestyle, like eating right, exercising regularly, and a minimum exposure to stress, can help boost fertility as well. A preconception visit to your doctor is also recommended in order to have you and your partner’s over-all health and fertility evaluated and for you to discuss and explore your options for fertility. Best of luck!

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  • CatZ

    I took clomid under my ob-gyne’s prescribed. My period starts aug 29 and i started taking clomid aug 30. Then i took pt test sept 26 ang it has 2 lines but the other line are fainted, then i took pt test again sept 30 ang it turned negative. Am I pregnant?

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  • CatZ

    My mistake, i took pt test on sept 28 not sept 30.

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