New Method of Fertilization Could Improve IVF Success Rates

on May 26, 2013

by Dr. Prabha Sahgal, MD

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However recent research has shown that a new method of fertilization could actually increase the odds of success through IVF. This new method is known as ICSI or Intracytoplasmic sperm injection.

Things are changing rapidly and there are numerous advancements today. A number of innovations are coming up in the field of science. The field of fertility has seen tremendous in the past few decades and a number of new techniques have come up such as in vitro fertilization. Such techniques have made things easier for many couples and they have successfully become parents albeit in an expensive manner with a few risks involved. Claim Your 20 Free Pregnancy Tests – Click Here

IVF Success Rate

Until now, the success rate of the IVF technique has been slightly low bordering at 40 percent. However recent research has shown that a new method of fertilization could actually increase the odds of success through IVF. This new method is known as ICSI or Intracytoplasmic sperm injection. This method is useful when the reason why you are not able to get pregnant is male infertility.

Intracytoplasmic Sperm Injection or ICSI

This method is used along with IVF and it has been shown that the success rates have increased when these two methods have been used together. In ICSI, the doctor will select sperm after examining a number of sperm under about 200 to 400 magnification. Once she selects the best sperm, she injects it into the egg. Of course, in IVF a number of embryos are produced. Thus, a few sperm are used and every selected egg is injected in the similar manner. The sperm selected are the best from the lot. They are normally shaped and healthy.


There is another procedure, which is more expensive than ICSI. However, it has shown better results than ICSI. This method is the IMSI or intracytoplasmic morphologically selected sperm injection. This method is generally not used initially. It is suggested only when IVF conducted with ICSI fails.

Recent Studies

Recently, a few scientists worked to compare these methods and find out which ones have the higher success rates. Over 9,000 cases of male infertility were examined in this study. Among these cases, a few were asked to choose ICSI with IVF and the others were asked to choose IMSI. Then the success rates were examined. It was shown that the success rate of IMSI was a little more than ICSI.

Further, the patients who chose ICSI with IVF and failed to get pregnant were asked to go for IMSI. This time it was found that the success rate increased by 56 percent. In patients who chose to go for ICSI again saw a success rate of pregnancy of around 38 percent. In the first group, delivery rate was 28 percent and in the second group, the delivery rate was 18 percent.


Thus, these studies show that you should consider going for ICSI along with IVF in order to tick the odds in your favor. Since IMSI is more expensive, it is not an ideal first line treatment. If, however, you fail with ICSI, instead of going for ICSI again you should go for IMSI. These two new methods of fertilization teamed with IVF have indeed increased the hopes of couples.

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New Method of Fertilization Could Improve IVF Success Rates, 5.0 out of 5 based on 5 ratings

Dr. Prabha Sahgal MD, is board certified in obstetrics and gynecology and subspecialty board certified in reproductive endocrinology and infertility. Dr. Sahgal holds a B.S. degree from MIT in molecular biology and currently serves on the ConceiveEasy board of directors.

  • Debbie

    Hello, my name is Debbie, and im believing if im not mistaken that its been about 2 weeks since i got my package in the mail. well, altho, i know it’s still too early to notice any changes from the pills and my body at the same time, it scared me a bit because my cycle started playing trick on me. i’ve been so irregular with my cycle for the past 3 years, and its just now getting back to normal starting this in 2013. out of no where, my cycle came early this month of june 2013 on the 19th which only lasted 3 days and followed by a real light spotting pinkish which only lasted for a few hours. does that show any signs of any improvements happening so far with my body and changes occuring from this pills? pLease let me know.

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