In Vitro Maturation a Better Alternative To IVF?

In Vitro Maturation a Better Alternative To IVF?

Infertility has sadly become very common today. Numerous couples suffer from infertility and end up undergoing various treatments for infertility in order to have children. Treatment usually begins with simple steps such as oral medications and injections.  Claim Your 20 Free Pregnancy Tests – Click Here

If these don’t work and the problem is severe, the doctor will advise you to go for any of the fertility treatments such as IUI and IVF. IVF or in vitro fertilization has the highest success rate and many couples have successfully become pregnant and given birth thanks to IVF. Because of its success rate and despite its expenses, IVF is a good idea for those who want to have a baby.


In in-vitro fertilization or IVF, the egg and the sperm are fused under laboratory conditions. If you are not able to produce mature eggs or if the male partner has abnormal sperm or both, donors may be used.

Once the eggs and the sperm are extracted, they are fused in a tube or a petri dish and allowed to grow until the embryo stage. After this, the embryos are implanted into the uterus of the mother.


IVM stands for in vitro maturation. It is more or less like IVF but with small differences, which actually account to a lot. In IVM, the immature eggs are retrieved. This means that the eggs extracted from the woman are not yet mature.

In IVM, ovarian stimulation fertility drugs may or may not be given. There is no compulsion. However, exposure to hCG is important. The eggs are grown in a medium in the lab to mature.

The medium is approximately the same as that used in IVF for growing embryos but the difference is that the medium for IVM also consists of hormones essential for the maturation of the eggs.

When IVM is Best

IVM has been used sometimes in particular cases. For example, women with PCOS have been advised to go for IVM. Also, some women are sensitive to the ovarian stimulation drugs and may develop ovarian hyperstimulation syndrome. IVM is a better option for such women too. Some cancer patients have also chosen IVM before undergoing chemotherapy in order to preserve their fertility.

Is IVM better than IVF?

Maybe. Some researchers have said that IVM can be helpful in cases where IVF has failed or where IVF is not a safer option. However, being hasty here will not help. The patients and the doctors must think about the benefits and the risks involved in going for IVM instead of IVF.

Not certain if IVM is safer

The problem here is that there is no sufficient data to prove that IVM is safer. This is because it has only been carried out a few times. This is the reason why the doctors may not want to go for this process. However, under some circumstances such as PCOS and ovarian hyperstimulation syndrome, this is the best bet.


Because of the lack of data, many people still consider IVF to be the better and safer choice. If IVF is not an option for you and you want to have babies, you should talk to your doctor so that he tells you about all the risks involved in IVM. Based on what you find out you can make an informed decision.

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Maureen Stephens, BS, RN
Maureen Stephens, BS, RN | ConceiveEasy
Ms. Stephens has spent over twenty years in the healthcare world, specializing in obstretical and medical/surgical nursing. She joined ConceiveEasy as she has a strong interest in educating and empowering women and promoting fertility awareness.