Clomid and Poly-Cystic Ovary Syndrome (PCOS)

on Jan 27, 2013

by Dr. Prabha Sahgal, MD

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One of the ways that physicians will help you manage PCOS is to help restore your fertility, perhaps by prescribing PCOS.

Women that suffer from Poly-Cystic Ovary Syndrome (PCOS) often experience reduced fertility and have difficulty conceiving. Clomid is a drug which stimulates ovulation. It is effective in causing ovulation 80% of the time and the success rate for impregnation is 40% over a three month trial. One of the ways that physicians will help you manage PCOS is to help restore your fertility, although it is important to note that not all sufferers have problems conceiving, only consider taking these drugs after exhausting all other possibilities. Claim Your 20 Free Pregnancy Tests – Click Here

How does Clomid work

Clomid or Serophene is a trademark for clomifene or clomiphene citrate which is a fertility drug that mimics oestrogen and causes ovulation. The most common dose is 50mg of Clomid taken in pill form, on day three to seven of your cycle and days five to nine. The beginning of your cycle is when your period starts. Clomid makes your body believe that you have low oestrogen levels. The brain thus sends a signal to your body which starts producing GnRH (gonadotropin-releasing hormone). This causes a release of Follicle-stimulating hormone (FSH) and Lutenizing Hormone (LH). This chain reaction results in the ovaries releasing more eggs.

Before starting Clomid

There are a couple of issues to be aware of before starting Clomid. Namely that this drug will only help if your fallopian tubes are undamaged and you are not suffering from an STI or other infection. Consult your doctor to ensure that your infertility is linked with your PCOS, and is not due to another preventable condition. Many women after a period of weight loss that has restored them to a healthy BMI, find that their cycles return to normal on their own and they are able to conceive. It also puts your body in a healthy position in which to carry and birth your baby. However, if this still doesn’t work then Clomid or another ovulation stimulating drug, may help.

The side effects of Clomid

The most common side-effects of Clomid affect less than 1% of users. These include abdominal pain, visual blurring, ovarian enlargement and hot flashes. Less common Clomid side effects include uterine bleeding, nausea, vomiting, alopecia and ovarian hyper stimulation syndrome. Some women report changes in their cervical mucus which make it hostile to sperm. In these cases you might want to find ways to increase its production. These are fairly rare though and side effects disappear as soon as you stop taking them. Do not take Clomid without consulting with a doctor who will closely measure your heath. The complications can be serious, but long term damage hopefully preventable.

After ending Clomid

If Clomid does not work for you then there are other steps, namely follicle-stimulating hormones injections (FSH) or in vitro fertilisation (IVF) that may help you in your effort to conceive. Alternatively if you did conceive, did you know that women on Clomid are ten times more likely to have twins, and have an increased chance of triplets? The increase in fertility through Clomid certainly brings with it some advantages (or disadvantages if the thought of triplets makes you a little wary), but it may be an option to help bring a little bundle of joy into your life.

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Clomid and Poly-Cystic Ovary Syndrome (PCOS), 4.9 out of 5 based on 8 ratings

Dr. Prabha Sahgal MD, is board certified in obstetrics and gynecology and subspecialty board certified in reproductive endocrinology and infertility. Dr. Sahgal holds a B.S. degree from MIT in molecular biology and currently serves on the ConceiveEasy board of directors.

  • Victoria

    I been trying to get pregnant since I was 16 and now I am two months away from my 21st Bday what could be going on?

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  • Dr. Christine Lee, MD

    There are a lot of factors to consider when trying to get pregnant including your eating habits, your lifestyle and probably any infections or diseases you may have that can hinder your plans of conceiving. The best way to go about this is to visit your doctor and have your overall health checked so you can be treated if you have any illness and have your fertility options discussed as well. You can also boost your fertility by eating right, avoiding tobacco, stress and excessive alcohol and by exercising regularly.

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  • Hello

    I am PCOS diagnosed in 2008, I had have very irregular periods but I got pregnant on Dec 2004 which he was conceived naturally. I was 21, not overweight and exercised regularly. Found out I was pregnant on Feb 2005, baby arrived early by almost 4 weeks. Now he is a very healthy and smart boy. Since Dec 2012 my partner and I had been trying to get pregnant with no success and decided to go to a fertility clinic, Dr. put me on a NO-Carb diet for one month, and it did not work. Then he put me on metformin and been taking it for 3 weeks. I expected my period on the 9th of April and did not get it. Call doctor and put me on provera, today May 1st I got my period, call doctor and on Friday I will start taking Clomid on Friday and I hope I will be pregnant by the end of May. We both are on our late 20s and eventho I have one child, I want to have at least 2 more. It will make us happier than what we are already. 😀

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  • nubian queen

    i have been trying to get pregnant for over a year, (am 26yrs), i did an hsg and other tests and am ok. My cycle is 24-25 days, i have tried calculating my most fertile days.. but that doesnt help.. am worried… would u advise that i took Clomid or are there any tests for me to do..

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  • Mphatsoe

    My sista is 25 years old and diagnosed with polycystic ovarian cyst nd she was operated because of severe rigt lower abdominal pain and cystectomy was done. My question is she going to have babies or not?

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